Coding
KRAB

Part:BBa_K2549055

Designed by: Rongrong Du   Group: iGEM18_Fudan   (2018-10-08)


KRAB

This part is a highly conserved region of 75 amino acids on the N-terminal of many zinc finger proteins. It was characterized as a strong transcriptional repressor by Bonventre etc. It can be served as a transcription repressor and fused to DNA binding domains to reduce the expression of specific genes. We include this part as it is required for the parts collection Part:BBa_K2549016 ~ Part:BBa_K2549043.

Sequence and Features


Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 12
    COMPATIBLE WITH RFC[12]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]
  • 1000
    COMPATIBLE WITH RFC[1000]


[edit]
Categories
//cds/transcriptionalregulator/repressor
Parameters
None